S0375

D-Saccharinsäure 1,4-Lacton Monohydrat

≥98.0% (HPLC)

• Synonym(e): D-Glucarsäure-1,4-lacton, D-Saccharolacton
• Empirische Formel (Hill-System): C₆H₈O₇ · H₂O
• CAS-Nummer: 61278-30-6
• Molekulargewicht: 210.14
• Beilstein: 85594
• MDL-Nummer: MFCD00149334
• UNSPSC-Code: 12352201
• PubChem Substanz-ID: 24899420
• NACRES: NA.25

Eigenschaften

• Assay: ≥98.0% (HPLC)
• Form: powder
• Verunreinigungen: ≤10.0% water (Karl Fischer)
• Farbe: white
• mp (Schmelzpunkt): 91 - 93 °C ((196 - 199 °F ))
• Löslichkeit: water: 50 mg/mL, clear, colorless to faintly yellow
• Lagertemp.: 2-8°C
• SMILES String: O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
• InChI: 1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
• InChIKey: NPFKVZHSFSFLPU-QGBSHYGGSA-N

Beschreibung

Allgemeine Beschreibung

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

Anwendung

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)