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RAB0447

Sigma-Aldrich

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit

for detection of phospho-stat3 (pTyr705) and pan-stat3 in human, mouse or rat cell and tissue lysates

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human, mouse, rat

Methode(n)

ELISA: suitable
capture ELISA: suitable

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)

Verwandte Kategorien

Allgemeine Beschreibung

Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

Immunogen

Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3

Anwendung

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Targeting the Hepatocyte Growth Factor Receptor to Overcome Resistance to Targeted Therapies
Embryonic Stem Cell Protocols, 25-60 (2019)
Hyo Jeong Kang et al.
Oncotarget, 8(16), 27263-27276 (2017-05-04)
The non-receptor tyrosine phosphatase SHP2 has scaffolding functions in signal transduction cascades downstream of growth receptors. A recent study suggested that SHP2 acts as a tumor suppressor during hepatocellular carcinoma (HCC) development. Herein we examined whether SHP2 links the HBx-NF-κB

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