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RAB0393
Human Oncostatin M (OSM) ELISA Kit
for serum, plasma, cell culture supernatants and urine
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About This Item
UNSPSC-Code:
41116158
NACRES:
NA.32
Empfohlene Produkte
Speziesreaktivität
human
Verpackung
kit of 96 wells (12 strips x 8 wells)
Methode(n)
ELISA: suitable
capture ELISA: suitable
Aufnahme
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 1.37-1000 pg/mL
Nachweisverfahren
colorimetric
Versandbedingung
wet ice
Lagertemp.
−20°C
Angaben zum Gen
human ... OSM(5008)
Allgemeine Beschreibung
Oncostatin M (OSM) is a multifunctional hematopoietic cytokine that belongs to the interleukin-6 (IL-6) cytokine family. Human OSM is produced by activated T lymphocytes and monocytes mainly during inflammatory disorders. OSM acts as a cell growth modulator. In addition, it also participates in low-density lipoprotein (LDL) receptor upregulation and induction of hematopoietic factors. OSM contributes to the inflammatory process, autoimmunity, and immunopathogenesis of cancers.
Immunogen
Recombinant Human OSM
Anwendung
The Human Oncostatin M (OSM) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Oncostatin M in serum, plasma, cell culture supernatants, and urine.
Sonstige Hinweise
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit-Komponenten auch einzeln erhältlich
Produkt-Nr.
Beschreibung
SDB
Signalwort
Warning
H-Sätze
P-Sätze
Gefahreneinstufungen
Met. Corr. 1
Lagerklassenschlüssel
8A - Combustible corrosive hazardous materials
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A Grenier et al.
Blood, 93(4), 1413-1421 (1999-02-09)
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine known in particular to induce the synthesis of acute-phase proteins by hepatocytes. Because human polymorphonuclear neutrophils (PMN) can secrete numerous cytokines, the potential production of OSM by PMN was investigated. Highly
Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.
Botelho FM
Journal of Immunology, 191, 1453-1464 (2013)
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