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R7382

Sigma-Aldrich

Rifampicin

powder or crystals, suitable for plant cell culture, BioReagent

Synonym(e):

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV, Rifampin, Rifamycin AMP

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About This Item

Empirische Formel (Hill-System):
C43H58N4O12
CAS-Nummer:
13292-46-1
Molekulargewicht:
822.94
Beilstein:
5723476
EG-Nummer:
236-312-0
MDL-Nummer:
MFCD00151389
UNSPSC-Code:
10171502
PubChem Substanz-ID:
24899391
NACRES:
NA.72

product name

Rifampicin, suitable for plant cell culture, BioReagent, ≥95% (HPLC), powder or crystals

Produktlinie

BioReagent

Assay

≥95% (HPLC)

Form

powder or crystals

Methode(n)

cell culture | plant: suitable

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria
mycobacteria

Anwendung(en)

agriculture

Wirkungsweise

protein synthesis | interferes

Lagertemp.

−20°C

SMILES String

CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O

InChI

1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1

InChIKey

JQXXHWHPUNPDRT-WLSIYKJHSA-N

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Allgemeine Beschreibung

Chemical structure: macrolide

Anwendung

Rifampicin, a rifamycin, is active against mycobacteria. Rifamycin, is also an inhibitor of chloroplast RNA polymerase and may be used to study chloroplast-level DNA transcription in plants.

Biochem./physiol. Wirkung

Hemmt den Zusammenschluss von DNA und Proteinen zu reifen Viruspartikeln.
Wirkungsweise: Inhibiert die Initialisierung der RNA-Synthese durch die Bindung an die β-Untereinheit der RNA-Polymerase.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.Product is sensitive to light and moisture. Store under inert gas.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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4′-Hydroxy-3′,5′-dimethoxyacetophenon 97%

Sigma-Aldrich

D134406

4′-Hydroxy-3′,5′-dimethoxyacetophenon

Rifamycin SV Natriumsalz potency: ≥ 900 IU/mg (anhydrous basis)

Sigma-Aldrich

R8626

Rifamycin SV Natriumsalz

CITCO ≥98% (HPLC), solid

Sigma-Aldrich

C6240

CITCO

Stephan Eberhard et al.
The Plant journal : for cell and molecular biology, 31(2), 149-160 (2002-07-18)
We performed a systematic investigation of the quantitative relationship between genome copy number, transcription, transcript abundance and synthesis of photosynthetic proteins in the chloroplast of the green algae Chlamydomonas reinhardtii grown either in mixotrophic or phototrophic conditions. The chloroplast gene
Anil Koul et al.
Nature chemical biology, 3(6), 323-324 (2007-05-15)
The diarylquinoline R207910 (TMC207) is a promising candidate in clinical development for the treatment of tuberculosis. Though R207910-resistant mycobacteria bear mutations in ATP synthase, the compound's precise target is not known. Here we establish by genetic, biochemical and binding assays
Samy Figueiredo et al.
Antimicrobial agents and chemotherapy, 53(6), 2657-2659 (2009-03-25)
Two clonally related Acinetobacter baumannii isolates, A1 and A2, were obtained from the same patient. Isolate A2, selected after an imipenem-containing treatment, showed reduced susceptibility to carbapenems. This resistance pattern was related to insertion of the ISAba1 element upstream of
Sandra V Kik et al.
The Journal of infectious diseases, 211 Suppl 2, S58-S66 (2015-03-15)
The potential available market (PAM) for new diagnostics for tuberculosis that meet the specifications of the high-priority target product profiles (TPPs) is currently unknown. We estimated the PAM in 2020 in 4 high-burden countries (South Africa, Brazil, China, and India)
Toril Lindbäck et al.
Veterinary research, 41(1), 8-8 (2009-10-03)
Media-based bacteriological testing will fail to detect non-culturable organisms and the risk of consuming viable but non-culturable (VBNC) Listeria monocytogenes is unknown. We have here studied whether L. monocytogenes obtained from seafoods, processing environment and clinical cases enter the VBNC
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