PLA0163

Rabbit anti-ATRX Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(e): ATP-dependent helicase ATRX, ATR2, DNA dependent ATPase and helicase, JMS, Juberg-Marsidi syndrome, MRX52, MRXHF1, RAD54, RAD54 homolog (S. cerevisiae), RAD54L, SFM1, SHS, X-linked, X-linked 52, X-linked helicase II, X-linked nuclear protein, XH2, XNP, ZNF-HX, Zinc finger helicase, alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog), alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog. S. cerevisiae), helicase 2, mental retardation
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Qualität: Powered by Bethyl Laboratories, Inc.
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: 1:500-1:2,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:1,000-1:5,000
• Hinterlegungsnummer: NP_000480.2
• UniProt-Hinterlegungsnummer: P46100
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: rabbit ... ATRX(546)

Beschreibung

Immunogen

The epitope recognized by PLA0163 maps to a region between residue 2442 and the C-terminus (residue 2492) of human alpha thalassemia/mental retardation syndrome X-linked using the numbering given in entry NP_000480.2 (GeneID 546).

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Sonstige Hinweise

ATRX (alpha-thalassemia mental retardation X-linked) is a chromatin remodeling protein and transacting regulator of globin gene expression that has been linked to several X-linked mental retardation syndromes and hematologic diseases such as myelodysplasia. ATRX possesses an ATPase/helicase domain and is related to the SWI/SNF family of proteins. Mutations in ATRX have been demonstrated to cause changes in DNA methylation patterns and gene expression important to development.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable