N6505

β-Nicotinamidadenin-dinucleotidphosphat-2′-Phosphat, reduziert Tetranatriumsalz

≥95% (HPLC)

• Synonym(e): β-NADPH, 2′-NADPH Hydrat, Coenzym II reduziert Tetranatriumsalz, Dihydronicotinamidadenin-dinucleotidphosphat Tetranatriumsalz, NADPH Na₄, TPNH₂ Na₄
• Empirische Formel (Hill-System): C₂₁H₂₆N₇Na₄O₁₇P₃ · xH₂O
• CAS-Nummer: 2646-71-1
• Molekulargewicht: 833.35 (anhydrous basis)
• MDL-Nummer: MFCD00036263
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24897780
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: chicken liver
• Qualitätsniveau: 200
• Assay: ≥95% (HPLC); ≥95% (spectrophotometric assay)
• Form: powder
• Löslichkeit: 10 mM NaOH: soluble-50 mg/mL, clear, faintly to light yellow
• Lagertemp.: −20°C
• SMILES String: [Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
• InChI: 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
• InChIKey: WYWWVJHQDVCHKF-MPUNMZHWSA-J

Beschreibung

Anwendung

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem./physiol. Wirkung

NADPH ist ein Elektronenspender und Cofaktor vieler Redox-Enzyme, einschließlich Stickoxid-Synthetase.

Angaben zur Herstellung

Enzymatically reduced.

Sonstige Hinweise

abgefüllt nach Gewicht des Feststoffs

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable