MAK063

L-Carnitine Assay Kit

sufficient for 100 colorimetric or fluorometric tests

• Synonym(e): Carnitine Quantification Kit
• UNSPSC-Code: 12161503
• NACRES: NA.84

Eigenschaften

• Verwendung: sufficient for 100 colorimetric or fluorometric tests
• Nachweisverfahren: colorimetric; fluorometric
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Carnitine is a metabolite that is synthesized from lysine and methionine. Carnitine is essential for fatty acid β-oxidation due to its role in fatty acid transport into the mitochondrial matrix via the carnitine/acylcarnitine shuttle. Carnitine exists in two stereoisomers but only the L-carnitine isomer is biologically active. Tissue levels of L-carnitine decrease with aging and decreased L-carnitine may contribute to age-related mitochondrial decline. The L-Carnitine Assay Kit is a simple convenient means of measuring free L-Carnitine in biological samples such as serum.

Anwendung

L-Carnitine Assay Kit has been used to determine the concentration of carnitine in serum samples.

Eignung

Suitable for the measurement of free L-Carnitine in biological samples such as tissue, cells and serum

Prinzip

L-carnitine concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/ fluorometric (λex = 535/λem = 587 nm) product, proportional to the L-carnitine present. Typical sensitivities of detection for this kit are 10 μM (colorimetric) and 1 μM (fluorometric). The normal range for serum L-Carnitine is between 10-70 μM.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H317,H319,H334,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): 188.6 °F - closed cup
• Flammpunkt (°C): 87 °C - closed cup