L2506

β-Lactoglobulin aus Kuhmilch

≥85% (PAGE), lyophilized powder

• Synonym(e): β-LG, Bos d 5, beta-LG
• CAS-Nummer: 9045-23-2
• EG-Nummer: 232-928-9
• MDL-Nummer: MFCD00130635
• UNSPSC-Code: 12352202
• NACRES: NA.61

Eigenschaften

• Biologische Quelle: bovine milk
• Qualitätsniveau: 200
• Assay: ≥85% (PAGE)
• Form: lyophilized powder
• Methode(n): titration: suitable
• UniProt-Hinterlegungsnummer: P02754
• Lagertemp.: 2-8°C
• Angaben zum Gen: bovine ... LGB(280838)

Beschreibung

Allgemeine Beschreibung

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation. β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics. Polymorphisms in the β-lactoglobulin modulates bovine milk production and composition.

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da,. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Anwendung

β-Lactoglobulin from bovine milk has been used:

• for the generation of calibration curve for protein solubility index
• in acid-base titration
• as a standard for surface hydrophobicity analysis

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Qualität

Contains β-lactoglobulins A and B which can be isolated chromatographically.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)