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I2285

Sigma-Aldrich

IPA-3

≥95% (HPLC), powder

Synonym(e):

1,1′-Disulfanediyldinaphthalen-2-ol

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About This Item

Empirische Formel (Hill-System):
C20H14O2S2
CAS-Nummer:
42521-82-4
Molekulargewicht:
350.45
MDL-Nummer:
MFCD00388917
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329815364
NACRES:
NA.77

Assay

≥95% (HPLC)

Form

powder

Farbe

off-white to yellow

Löslichkeit

DMSO: >20 mg/mL
H2O: insoluble

Lagertemp.

2-8°C

SMILES String

Oc1ccc2ccccc2c1SSc3c(O)ccc4ccccc34

InChI

1S/C20H14O2S2/c21-17-11-9-13-5-1-3-7-15(13)19(17)23-24-20-16-8-4-2-6-14(16)10-12-18(20)22/h1-12,21-22H

InChIKey

RFAXLXKIAKIUDT-UHFFFAOYSA-N

Biochem./physiol. Wirkung

IPA-3 is an allosteric inhibitor of Pak1. It binds to autoinhibitory domain of Pak1 (p21 activated kinase), highly selective amongst kinases. Pak1 is implicated in tumorigenesis and metastasis.

Piktogramme

CorrosionEnvironment
GHS05,GHS09

Signalwort

Danger

H-Sätze

H318,H410

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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