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F5006
2-Fluor-2-Desoxy-D-Glucose
glycosylation inhibitor, glucose analog
Synonym(e):
2-Deoxy-2-fluor-D-glucose, FDG
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About This Item
Empirische Formel (Hill-System):
C6H11FO5
CAS-Nummer:
Molekulargewicht:
182.15
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.32
Empfohlene Produkte
Qualitätsniveau
Lagertemp.
2-8°C
SMILES String
OCC1OC(O)C(F)C(O)C1O
InChI
1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2
InChIKey
ZCXUVYAZINUVJD-UHFFFAOYSA-N
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Allgemeine Beschreibung
2-Fluoro-2-deoxy-D-glucose is non-toxic and a structural analog of glucose, significantly inhibiting glycosylation. As a glucose analog, uptake of 2-Fluoro-2-deoxy-D-glucose is rapid in brain and heart cells.
2-Fluoro-2-deoxy-D-glucose can be taken up by cells but does not undergo metabolic glycolysis.
2-Fluoro-2-deoxy-D-glucose can be taken up by cells but does not undergo metabolic glycolysis.
Anwendung
2-Fluoro-2-deoxy-D-glucose is used as a tracer for rapid tumor detection. It is used as a glucose analog to study glucose uptake in mice with radiation and burn injuries. Oncology therapy studies use FDG in combination with PET (Positron Emission Topography)
Biochem./physiol. Wirkung
Glucose analog that inhibits cellular glycosylation.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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