F2252
L-(−)-Fucose
≥98% (GC)
Synonym(e):
6-Deoxy-L-galactose
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Alle Fotos(5)
About This Item
Empirische Formel (Hill-System):
C6H12O5
CAS-Nummer:
Molekulargewicht:
164.16
Beilstein:
1723321
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.25
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Qualitätsniveau
Assay
≥98% (GC)
Form
powder
Methode(n)
gas chromatography (GC): suitable
Farbe
white
mp (Schmelzpunkt)
150-153 °C (lit.)
Löslichkeit
H2O: soluble 50 mg/mL, clear to very slightly hazy
SMILES String
C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
InChI
1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1
InChIKey
PNNNRSAQSRJVSB-KCDKBNATSA-N
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Allgemeine Beschreibung
L-Fucose, a natural monosaccharide found in mammals, is an important component of several N- and O-linked glycans and glycolipids.
Anwendung
L-(−)-Fucose has been used:
- as the non-haptenic sugar in lectin bead-binding assay to study its effects on the binding of immobilized lectins like peanut agglutinin (PNA) and Dolichos biflorus agglutinin (DBA)
- as an internal standard to dilute the enzymatic hydrolysates for analytical methods
- in the synthesis of fucosyl thioglycoside
Biochem./physiol. Wirkung
L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. L-Fucose is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis.
L-Fucose is broadly used as a food additive. It possesses anti-inflammatory effects. It can inhibit the cutaneous immune reaction and alveolar macrophage priming. L-fucose can also suppress tumor growth and tumorigenesis.
Sonstige Hinweise
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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By using a non-cancer and a cancer cell line originally from the same tissue (colon), coupled with testing lectins for cell binding and for their effects on these cell lines in culture, this study describes a simple multi-parameter approach that
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