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Merck

F0806

Sigma-Aldrich

Factor IX human

aqueous glycerol solution, ≥145 units/mg protein

Synonym(e):

Christmas factor, Plasma thromboplastin component

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352202
NACRES:
NA.61

Biologische Quelle

human

Qualitätsniveau

Form

aqueous glycerol solution

Spezifische Aktivität

≥145 units/mg protein

Mol-Gew.

55 kDa

Methode(n)

ligand binding assay: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... F9(2158)

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Allgemeine Beschreibung

Factor IX is a 55 kDa single chain vitamin K-dependent plasma zymogen which plays a key role in the intrinsic and extrinsic blood coagulation systems.

Anwendung

Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).

Verlinkung

View this factors role in the Coagulation Cascade

Einheitendefinition

One unit is equivalent to the Factor IX activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.

Physikalische Form

Aqueous solution containing 50% (v/v) glycerol

Haftungsausschluss

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Continuous Active State of Coagulation System in Patients With Nonthrombotic Inflammatory Bowel Disease.
Alkim H., et al.
Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2011)
Double trouble: Duchenne muscular dystrophy and hemophilia.
Muge Gokce et al.
Pediatric blood & cancer, 60(3), 525-525 (2012-12-21)
Sweta Gupta et al.
British journal of haematology, 161(3), 424-433 (2013-02-26)
This study prospectively compared the effect of secondary prophylaxis to episodic treatment on target joint (TJ) range of motion (ROM), number of joint haemorrhages and new TJ development in patients with moderate or severe haemophilia. Two-hundred and eighty-six males, 17%
History of prophylaxis.
E Berntorp
Haemophilia : the official journal of the World Federation of Hemophilia, 19(2), 163-165 (2013-02-20)
Keiichiro Kume et al.
Internal medicine (Tokyo, Japan), 46(17), 1323-1329 (2007-09-11)
Recent investigations suggest that activation of coagulation and fibrinolysis occurs in patients with ulcerative colitis (UC). However, the role of the hypercoagulable state in UC has not been determined. On the other hand, there are no reports dealing with coagulation

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