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D7408
2′,5′-Dideoxyadenosine
≥95% (HPLC), solid
Synonym(e):
2ʹ,5ʹ-dd-Ado, NSC 95943
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About This Item
Empfohlene Produkte
Qualitätsniveau
Assay
≥95% (HPLC)
Form
solid
Farbe
white
Löslichkeit
DMSO: soluble
Lagertemp.
−20°C
SMILES String
C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23
InChI
1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
InChIKey
FFHPXOJTVQDVMO-DSYKOEDSSA-N
Angaben zum Gen
rat ... Adcy2(81636)
Anwendung
2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).
Biochem./physiol. Wirkung
Cell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.
Leistungsmerkmale und Vorteile
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Rekonstituierung
Store at −20 °C after reconstitution.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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