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C5423

Sigma-Aldrich

Clenbuterol -hydrochlorid

≥95% (TLC), powder, β2-adrenoceptor agonist

Synonym(e):

4-Amino-α-(tert.-butylaminomethyl)-3,5-dichlorbenzylalkohol -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C12H18Cl2N2O · HCl
CAS-Nummer:
21898-19-1
Molekulargewicht:
313.65
EG-Nummer:
244-643-7
MDL-Nummer:
MFCD00083280
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24892782
NACRES:
NA.77

product name

Clenbuterol -hydrochlorid, ≥95%

Qualitätsniveau

200

Assay

≥95%

Form

powder

drug control

Home Office Schedule 4.2

Lagertemp.

2-8°C

SMILES String

Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1

InChI

1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

InChIKey

OPXKTCUYRHXSBK-UHFFFAOYSA-N

Angaben zum Gen

human ... ADRB2(154)

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Anwendung

Clenbuterol hydrochloride has been used:
  • as an agonist for β-adrenergic receptor (β-AR) from chick skeletal muscle
  • to induce hypertrophic effects in masseter, digastric, and temporalis muscles of rat
  • as a reference β-agonist standard in tandem mass spectrometry(MS-MS)

Biochem./physiol. Wirkung

Clenbuterol hydrochloride is a β2-adrenoceptor agonist and bronchodilator. It is effective in improving peak expiratory flow rate (PEFR) in asthma patients. Clenbuterol is also a performance-enhancing drug as it stimulates the central nervous system and improves oxygen transport. Clenbuterol elicits cardio protective functionality in patients with dilated cardiomyopathy.

Anwendung

Produkt-Nr.
Beschreibung
Preisangaben

G004337

HPLC Analysis of Beta-Receptor Agonist Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004431

LC/MS Analysis of Clenbuterol In Plasma on Astec® CHIROBIOTIC® T with Phospholipid Removal using HybridSPE® Phospholipid, application for SPE, application for LC-MS

G004245

LC/MS Analysis of Clenbuterol Enantiomers in Plasma on Astec® CHIROBIOTIC® T after SPE using HybridSPE®-Phospholipid, application for HPLC

G004493

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T, application for HPLC

G004596

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® T2, application for HPLC

G004621

HPLC Analysis of Clenbuterol Enantiomers on Astec® CHIROBIOTIC® V, application for HPLC

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H351,H360FD

Gefahreneinstufungen

Carc. 2 - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

C A Izeboud et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 48(9), 497-502 (1999-10-16)
To investigate the suppressive effects of the beta-agonist clenbuterol on the release of TNF-alpha and IL-6 in a lipopolysaccharide (LPS)-model of inflammation, both in vitro and in vivo. Human U-937 cell line (monocyte-derived macrophages), and male Wistar rats (200-250 g).
Jelka Pleadin et al.
Meat science, 86(3), 733-737 (2010-07-30)
The aim of this study was to determine the level of clenbuterol residues in muscle tissue of pigs after repeat administration in a growth-promoting dose. An anabolic dose of clenbuterol (20 μg/kg body mass per day) was administered orally to
I Semkova et al.
Brain research. Brain research reviews, 30(2), 176-188 (1999-10-19)
Neurotrophins and other neurotrophic factors have been shown to support the survival and differentiation of many neuronal populations of the central and peripheral nervous system. Therefore, administering neurotrophic factors could represent an alternative strategy for the treatment of acute and
Structural characterization of a new form of clenbuterol, a well-known decongestant and bronchodilator also used as a performance-enhancing drug
Toro R, et al.
Powder Diffraction, 28(2), 63-67 (2013)
A trial of clenbuterol in bronchial asthma.
Anderson G and Wilkins E
Thorax, 32(6), 717-719 (1977)
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