C265
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse
clone 6G9, purified immunoglobulin, buffered aqueous solution
Synonym(e):
Anti-CAMKA, Anti-CaMKIINalpha, Anti-CaMKIIalpha, Anti-MRD53, Anti-MRT63
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Konjugat:
unconjugated
application:
IF
WB
WB
Klon:
6G9, monoclonal
Speziesreaktivität:
rat, mouse
citations:
19
Methode(n):
indirect immunofluorescence: suitable using rat hippocampus
western blot: 0.5-1.0 μg/mL
western blot: 0.5-1.0 μg/mL
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Konjugat
unconjugated
Antikörperform
purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
6G9, monoclonal
Form
buffered aqueous solution
Mol-Gew.
antigen ~50 kDa
Speziesreaktivität
rat, mouse
Methode(n)
indirect immunofluorescence: suitable using rat hippocampus
western blot: 0.5-1.0 μg/mL
Isotyp
IgG1
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Lagertemp.
−20°C
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
rat ... Camk2a(25400)
Allgemeine Beschreibung
CaM Kinase II α is a Ca2+/calmodulin-dependent kinase that belongs to the serine/threonine protein kinases family. It facilitates the regulation of NMDAR-dependent AMPA receptor trafficking to the synapses. Mouse anti-CaM kinase II α antibody reacts specifically with phosphorylated and non-phosphorylated forms of native and recombinant CaM (Ca2+/calmodulin-dependent) kinase II α subunit in rats. The product has shown no reactivity for phosphorylated or non-phosphorylated β subunit (60kD).
Immunogen
partially purified rat CaM kinase II.
Anwendung
Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse has been used in immunohistochemistry and western blotting.
Physikalische Form
Solution in phosphate buffered saline containing 0.05% sodium azide
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
nwg
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Naohiro Kon et al.
Genes & development, 28(10), 1101-1110 (2014-05-17)
Daily behavioral rhythms in mammals are governed by the central circadian clock, located in the suprachiasmatic nucleus (SCN). The behavioral rhythms persist even in constant darkness, with a stable activity time due to coupling between two oscillators that determine the
Joana S Ferreira et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(22), 8462-8479 (2015-06-05)
NMDA receptors play a central role in shaping the strength of synaptic connections throughout development and in mediating synaptic plasticity mechanisms that underlie some forms of learning and memory formation in the CNS. In the hippocampus and the neocortex, GluN1
Esther Del Cid-Pellitero et al.
Frontiers in systems neuroscience, 11, 17-17 (2017-04-15)
Neuronal activity is regulated in a homeostatic manner through changes in inhibitory GABA and excitatory glutamate (Glu) AMPA (A) receptors (GluARs). Using immunofluorescent staining, we examined whether calcium/calmodulin-dependent protein kinase IIα (CaMKIIα)-labeled (+) excitatory neurons in the barrel cortex undergo
Roshni Ramachandran et al.
Cephalalgia : an international journal of headache, 38(6), 1057-1070 (2017-07-26)
Background A common characteristic of migraine-inducing substances is that they cause headache and no pain in other areas of the body. Few studies have compared pain mechanisms in the trigeminal and spinal systems and, so far, no major differences have
Wen Fong Ooi et al.
PLoS genetics, 9(9), e1003795-e1003795 (2013-09-27)
Burkholderia pseudomallei (Bp), the causative agent of the often-deadly infectious disease melioidosis, contains one of the largest prokaryotic genomes sequenced to date, at 7.2 Mb with two large circular chromosomes (1 and 2). To comprehensively delineate the Bp transcriptome, we
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