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C0742

Sigma-Aldrich

CKI-7 dihydrochloride

≥98% (HPLC), solid

Synonym(e):

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

Empirische Formel (Hill-System):
C11H12ClN3O2S · 2HCl
CAS-Nummer:
1177141-67-1
Molekulargewicht:
358.67
MDL-Nummer:
MFCD00897689
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24724430
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

solid

Lagerbedingungen

desiccated

Farbe

white to light tan

Löslichkeit

H2O: >5 mg/mL

Lagertemp.

−20°C

SMILES String

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChIKey

JUAVTXYOCISSSL-UHFFFAOYSA-N

Biochem./physiol. Wirkung

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

Vorsicht

Material is hygroscopic

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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