B7686

1(S),9(R)-(−)-Bicuculline methchloride

≥97% (HPLC), powder

• Lineare Formel: C₂₁H₂₀NO₆Cl
• CAS-Nummer: 38641-83-7
• Molekulargewicht: 417.84
• MDL-Nummer: MFCD00055233
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329773300
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (HPLC)
• Form: powder
• Löslichkeit: H₂O: >10 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: [Cl-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45
• InChI: 1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1
• InChIKey: RLJKFAMYSYWMND-GRTNUQQKSA-M

Beschreibung

Biochem./physiol. Wirkung

1(S),9(R)-(−)-Bicuculline methchloride is a GABA_A receptor antagonist, which blocks Ca²⁺-activated potassium (SK) channels.

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)