Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

B2805

Sigma-Aldrich

Bone Morphogenetic Protein 6 human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

Synonym(e):

BMP-6

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

MDL-Nummer:
MFCD02097809
UNSPSC-Code:
12352202
NACRES:
NA.32

Biologische Quelle

human

Qualitätsniveau

100

Rekombinant

expressed in NSO cells

Assay

>95% (SDS-PAGE)

Form

lyophilized powder

Wirksamkeit

0.05-0.15 μg/mL ED50

Mol-Gew.

30–38 kDa

Verpackung

pkg of 20 μg

Lagerbedingungen

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

endotoxin, tested

UniProt-Hinterlegungsnummer

P22004

Lagertemp.

−20°C

Angaben zum Gen

human ... BMP6(654)

Verwandte Kategorien

Biochem./physiol. Wirkung

Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.

Physikalische Form

Lyophilized from 200 ul 0.2 μm filtered solution in 40% acetonitrile, 0.1% trifluoroacetic acid containing 50ug bovine serum albumin per 1 ug as a carrier protein.

Hinweis zur Analyse

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Bone morphogenetic proteins and their receptors: potential functions in the brain.
Ebendal, T., et al
The Journal of Neuroscience, 51, 139-146 (1998)
Christine E McLaren et al.
Hepatology (Baltimore, Md.), 62(2), 429-439 (2015-01-22)
To identify polymorphisms associated with variability of iron overload severity in HFE-associated hemochromatosis, we performed exome sequencing of DNA from 35 male HFE C282Y homozygotes with either markedly increased iron stores (n = 22; cases) or with normal or mildly increased iron
Stephanie Arndt et al.
Gut, 64(6), 973-981 (2014-07-12)
Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease (NAFLD) and its advanced form non-alcoholic steatohepatitis (NASH) is elusive. The aim of this
Hiroshi Kawabata et al.
Experimental hematology, 43(5), 404-413 (2015-01-31)
Hepcidin is the central regulator of systemic iron homeostasis; dysregulation of hepcidin expression causes various iron metabolic disorders, including hereditary hemochromatosis and anemia of inflammation. To identify molecules that modulate hepcidin expression, we developed a bioassay system for hepcidin gene
Zhu Xishan et al.
Journal of experimental & clinical cancer research : CR, 30, 47-47 (2011-05-04)
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.