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Merck

A5139

Sigma-Aldrich

Asp-Phe-OMe

≥98%

Synonym(e):

N-(L-α-Aspartyl)-L-phenylalanin-methylester, Asp-Phe-Methylester, Aspartam

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About This Item

Lineare Formel:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
CAS-Nummer:
Molekulargewicht:
294.30
Beilstein:
2223850
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352108
PubChem Substanz-ID:
NACRES:
NA.26

Qualitätsniveau

Assay

≥98%

Form

powder

Süße

160-200 × sucrose

Farbe

white to off-white

Lagertemp.

2-8°C

SMILES String

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

InChIKey

IAOZJIPTCAWIRG-QWRGUYRKSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Asp-Phe methyl ester (aspartame, APM, ASP), a dipeptide ester, is made up of phenyl alanine and aspartic acid. Its genotoxic effects have been investigated. Its interaction with certain hydrocolloids has been studied.

Anwendung

Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester.

Biochem./physiol. Wirkung

Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sugar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid factor activity. Asp-Phe methyl ester is being studied for its effect on thrombin activity and blood clotting.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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Kunden haben sich ebenfalls angesehen

Aspartame: in perspective.
Caseley J and Dixon W.
Nutrition & Food Science, 31(1), 23-27 (2001)
Kate S Collison et al.
Nutrition & metabolism, 9(1), 58-58 (2012-06-16)
Recent evidence suggests that the effects of certain food additives may be synergistic or additive. Aspartame (ASP) and Monosodium Glutamate (MSG) are ubiquitous food additives with a common moiety: both contain acidic amino acids which can act as neurotransmitters, interacting
Interaction of aspartame with selected hydrocolloids: solubility of aspartame.
Wafwoyo W, et al.
Food Hydrocolloids, 13(4), 299-302 (1999)
Kate S Collison et al.
Nutrition & metabolism, 10, 44-44 (2013-06-21)
The human diet has altered markedly during the past four decades, with the introduction of Trans hydrogenated fat, which extended the shelf-life of dietary oils and promoted a dramatic increase in elaidic acid (Trans-18.1) consumption. Food additives such as monosodium
Genotoxicity of aspartame.
Rencuzogullari E, et al.
Drug and Chemical Toxicology, 27(3), 257-268 (2004)

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