465R-1

TROP2 (EP431) Rabbit Monoclonal Primary Antibody

• Synonym(e): Trophoblast Antigen 2
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP431, monoclonal
• Beschreibung: For In Vitro Diagnostic Use in Select Regions
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (465R-14); vial of 0.1 mL concentrate Research Use Only (465R-14-RUO); vial of 0.5 mL concentrate (465R-15); vial of 1.0 mL concentrate (465R-16); vial of 1.0 mL concentrate Research Use Only (465R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (465R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (465R-17); vial of 7.0 mL pre-dilute ready-to-use (465R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (465R-18-RUO)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotyp: IgG
• Kontrolle: papillary carcinoma of thyroid
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: cytoplasmic, membranous
• Angaben zum Gen: human ... TACSTD2(4070)

Beschreibung

Allgemeine Beschreibung

Trophoblast antigen 2 (TROP2) is a transmembrane glycoprotein that transduces intracellular calcium signals. The overexpression of TROP2 has been linked to tumor progression due to its involvement in the regulation of multiple vital cell processes including migration, proliferation, and invasion. TROP2 exhibits strong, diffuse staining in papillary thyroid carcinoma, while staining in other thyroid lesions, such as follicular thyroid adenomas and carcinomas, is limited to rare, focal, or scattered cells. An increase in TROP2 expression has also been observed in colorectal carcinomas and ovarian serous carcinomas compared to non-neoplastic ovary and colon.

Qualität

IVD

IVD

IVD

RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable