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Sigma-Aldrich

6-Dodecanoyl-N,N-dimethyl-2-naphthylamin

suitable for fluorescence, ≥97.0% (HPLC)

Synonym(e):

2-(Dimethylamino)-6-dodecanoyl-naphthalin, N,N-Dimethyl-6-dodecanoyl-2-naphthylamin, Laurdan

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About This Item

Empirische Formel (Hill-System):
C24H35NO
CAS-Nummer:
74515-25-6
Molekulargewicht:
353.54
Beilstein:
7379104
MDL-Nummer:
MFCD00467560
UNSPSC-Code:
12352116
PubChem Substanz-ID:
57649941
NACRES:
NA.32

Qualitätsniveau

100

Assay

≥97.0% (HPLC)

mp (Schmelzpunkt)

88 °C (lit.)

Löslichkeit

DMF: soluble
acetonitrile: soluble
methanol: soluble

Fluoreszenz

λex 366 nm; λem 497 nm in methanol

Eignung

suitable for fluorescence

SMILES String

CCCCCCCCCCCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3

InChIKey

JHDGGIDITFLRJY-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

6-Dodecanoyl-N,N-dimethyl-2-naphthylamine (Laurdan) is a fluorescent probe used to study membrane structure, order and dynamic processes such as fluidity.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Fluoreszierende Membran-Sonde

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Simmon Hofstetter et al.
Journal of microbiological methods, 91(1), 93-100 (2012-08-14)
A method for measuring the fluidity of inner membranes of populations of endospores of Clostridium spp. with a fluorescent dye was developed. Cells of Clostridium beijerinckii ATCC 8260 and Clostridium sporogenes ATCC 7955 were allowed to sporulate in the presence
L A Bagatolli et al.
Biochimica et biophysica acta, 1325(1), 80-90 (1997-04-03)
Laurdan (6-dodecanoyl-2-dimethylamine-naphthalene) is a fluorescent membrane probe of recent characterization. It was shown that this probe discriminates between phase transitions, phase fluctuations and the coexistence of phase domains in phospholipid multilamellar aggregates. We measured the excitation and emission generalized polarization
Adéla Melcrová et al.
Scientific reports, 6, 38035-38035 (2016-12-03)
Understanding interactions of calcium with lipid membranes at the molecular level is of great importance in light of their involvement in calcium signaling, association of proteins with cellular membranes, and membrane fusion. We quantify these interactions in detail by employing
L.I. Hellgren
Plant Physiology and Biochemistry, 34, 455-455 (1996)
Luis A Bagatolli et al.
Biomolecules, 9(11) (2019-11-07)
We propose that active metabolic processes may regulate structural changes in biological membranes via the physical state of cell water. This proposition is based on recent results obtained from our group in yeast cells displaying glycolytic oscillations, where we demonstrated
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