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04668

Sigma-Aldrich

O-Phospho-L-homoserin Lithiumsalz

≥95% (TLC)

Synonym(e):

O-Phosphono-L-homoserin Lithiumsalz, L-2-Amino-4-hydroxybuttersäure-4-phosphat Lithiumsalz, L-Homoserin-O-phosphat Lithiumsalz, H-Hse(PO3H2)-OH

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About This Item

Empirische Formel (Hill-System):
C4H10NO6P · xLi+
CAS-Nummer:
4210-66-6
Molekulargewicht:
199.10 (free acid basis)
UNSPSC-Code:
12352209
NACRES:
NA.26

Assay

≥95% (TLC)

Form

powder

Optische Aktivität

[α]/D -18.0±2.0°, c = 1 in H2O

Farbe

white to off-white

Lagertemp.

−20°C

InChI

1S/C4H10NO6P/c5-3(4(6)7)1-2-11-12(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1

InChIKey

FXDNYOANAXWZHG-VKHMYHEASA-N

Biochem./physiol. Wirkung

Metabolite in glycine, serine and threonine metabolism. In higher plants, O-phosphohomoserine represents a branch point between the methionine and threonine biosynthetic pathways.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Hongtao Li et al.
Science (New York, N.Y.), 315(5814), 1000-1003 (2007-02-17)
Pathogenic bacteria use the type III secretion system to deliver effector proteins into host cells to modulate the host signaling pathways. In this study, the Shigella type III effector OspF was shown to inactivate mitogen-activated protein kinases (MAPKs) [extracellular signal-regulated
T Zhou et al.
Structure (London, England : 1993), 8(12), 1247-1257 (2001-02-24)
Homoserine kinase (HSK) catalyzes an important step in the threonine biosynthesis pathway. It belongs to a large yet unique class of small metabolite kinases, the GHMP kinase superfamily. Members in the GHMP superfamily participate in several essential metabolic pathways, such
Oliver Kreft et al.
Plant physiology, 131(4), 1843-1854 (2003-04-15)
In plants, metabolic pathways leading to methionine (Met) and threonine diverge at the level of their common substrate, O-phosphohomoserine (OPHS). To investigate the regulation of this branch point, we engineered transgenic potato (Solanum tuberosum) plants affected in cystathionine gamma-synthase (CgS)
D Bartlem et al.
Plant physiology, 123(1), 101-110 (2000-05-12)
In higher plants, O-phosphohomoserine (OPH) represents a branch point between the methionine (Met) and threonine (Thr) biosynthetic pathways. It is believed that the enzymes Thr synthase (TS) and cystathionine gamma-synthase (CGS) actively compete for the OPH substrate for Thr and
G E Gilbert et al.
Biochemistry, 32(37), 9577-9585 (1993-09-21)
Phosphatidylserine, a negatively charged lipid, is exposed on the platelet membrane following cell stimulation, correlating with the expression of factor VIII receptors. We have explored the importance of the negative electrostatic potential of phosphatidylserine vs chemical moieties of phosphatidylserine for
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