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Y0001489

Methacrylsäure-2-(dimethylamino)-ethylester

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

2-(Dimethylamino)-ethyl-methacrylat

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About This Item

Lineare Formel:
CH2=C(CH3)COOCH2CH2N(CH3)2
CAS-Nummer:
Molekulargewicht:
157.21
Beilstein:
1757048
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

Dampfdichte

5.4 (vs air)

Dampfdruck

<1 mmHg ( 25 °C)

API-Familie

amino methacrylate copolymer, basic butylated methacrylate copolymer, copolymers

Hersteller/Markenname

EDQM

Brechungsindex

n20/D 1.439 (lit.)

bp

182-192 °C (lit.)

Dichte

0.933 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CN(C)CCOC(=O)C(C)=C

InChI

1S/C8H15NO2/c1-7(2)8(10)11-6-5-9(3)4/h1,5-6H2,2-4H3

InChIKey

JKNCOURZONDCGV-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

2-(Dimethylamino)ethyl methacrylate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

CorrosionExclamation mark

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flammpunkt (°F)

147.2 °F - closed cup

Flammpunkt (°C)

64 °C - closed cup


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Tomohiro Kamada et al.
Colloids and surfaces. B, Biointerfaces, 123, 878-886 (2014-12-04)
Brushes of a polymer, namely poly(carboxymethylbetaine) (PCMB), were fabricated on silicon wafers by reversible addition-fragmentation chain-transfer (RAFT) polymerization using a surface-confined RAFT agent having an aromatic group at its bottom. The polymer brush showed effective suppression of the non-specific adsorption
Makoto Ishida et al.
Drug development and industrial pharmacy, 40(8), 1054-1064 (2013-06-21)
Abstract The applicability of porous spherical silica (PSS) was evaluated as core particles for pharmaceutical products by comparing it with commercial core particles such as mannitol (NP-108), sucrose and microcrystalline cellulose spheres. We investigated the physical properties of core particles
Chia-Wen Lo et al.
PloS one, 9(5), e97627-e97627 (2014-05-16)
Ultrasound (US) has been found to facilitate the transport of DNA across cell membranes. However, the transfection efficiency is generally low, and the expression duration of the transfected gene is brief. In this study, a tertiary polycation, Poly(2-(dimethylamino) ethyl methacrylate)
Íris Duarte et al.
Pharmaceutical research, 32(1), 222-237 (2014-08-20)
To present a new screening methodology intended to be used in the early development of spray-dried amorphous solid dispersions. A model that combines thermodynamic, kinetic and manufacturing considerations was implemented to obtain estimates of the miscibility and phase behavior of
Kateřina Punčochová et al.
International journal of pharmaceutics, 469(1), 159-167 (2014-04-23)
The objective of this study was to investigate the effect of different polymeric carriers in solid dispersions with an active pharmaceutical ingredient (API) on their water vapour sorption equilibria and the influence of the API-polymer interactions on the dissolution rate

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