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Y0000039

Natriumascorbat

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(+)-Natrium-L-ascorbat, L(+)-Ascorbinsäure Natriumsalz, Vitamin C Natriumsalz

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About This Item

Empirische Formel (Hill-System):
C6H7NaO6
CAS-Nummer:
Molekulargewicht:
198.11
Beilstein:
3767246
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Biologische Quelle

synthetic

Qualität

pharmaceutical primary standard

Agentur

EP

API-Familie

sodium ascorbate

Form

solid

Hersteller/Markenname

EDQM

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp (Schmelzpunkt)

220 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChIKey

PPASLZSBLFJQEF-RXSVEWSESA-M

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Sodium ascorbate may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1


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Die Dokumentenbibliothek aufrufen

, Book author=
Handbook of Pharmaceutical Excipients (2009)
Sodium ascorbate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6997-6998 (2019)
Marina A Kozuleva et al.
FEBS letters, 588(23), 4364-4368 (2014-10-15)
O2 reduction was investigated in photosystem I (PSI) complexes isolated from cyanobacteria Synechocystis sp. PCC 6803 wild type (WT) and menB mutant strain, which is unable to synthesize phylloquinone and contains plastoquinone at the quinone-binding site A1. PSI complexes from
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
Gábor Bánhegyi et al.
Biochimica et biophysica acta, 1843(9), 1909-1916 (2014-06-08)
Beyond its general role as antioxidant, specific functions of ascorbate are compartmentalized within the eukaryotic cell. The list of organelle-specific functions of ascorbate has been recently expanded with the epigenetic role exerted as a cofactor for DNA and histone demethylases

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