SMB01381

SAICAriboside

≥95% (HPLC), from synthetic, solid

• Synonym(e): N-Succinyl-5-aminoimidazole-4-carboxamide Ribose
• Empirische Formel (Hill-System): C₁₃H₁₈N₄O₉
• CAS-Nummer: 17388-80-6
• Molekulargewicht: 374.30
• MDL-Nummer: MFCD31563062
• UNSPSC-Code: 12352211
• UNSPSC-Code: 12352200
• NACRES: NA.26

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Assay: ≥95% (HPLC)
• Form: solid
• Farbe: white to beige
• mp (Schmelzpunkt): 130-135 °C
• Lagertemp.: 2-8°C
• SMILES String: NC1=C(C(N[C@H](C(O)=O)CC(O)=O)=O)N=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2
• InChI: 1S/C13H18N4O9/c14-10-7(11(23)16-4(13(24)25)1-6(19)20)15-3-17(10)12-9(22)8(21)5(2-18)26-12/h3-5,8-9,12,18,21-22H,1-2,14H2,(H,16,23)(H,19,20)(H,24,25)/t4-,5+,8+,9+,12+/m0/s1

Beschreibung

Allgemeine Beschreibung

SAICAR (a ribotide) can lose its phosphate group leading to the appearance of a riboside known as succinylaminoimidazolecarboxamide riboside (SAICAriboside or SAICAr) in cerebrospinal fluid, in urine, and, to a lesser extent, in plasma. SAICAriboside is characteristic of ADSL, a heritable deficiency of the enzyme adenylosuccinate lyase (ASL or adenylosuccinase) responsible for metabolizing SAICAR (SZMP) to AICAR (ZMP) and adenylosuccinate (SAMP) to AMP. ASL deficiency causes increased SAICAR & SAMP, and their corresponding rephosphorylated products SAICAr & succinyladenosine (S-Ado).

Lagerung und Haltbarkeit

Heat sensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable