PHR2886

Spironolacton

pharmaceutical secondary standard, certified reference material

• Synonym(e): Spironolacton, 4-Pregnen-21-säure-17α-ol-3-on-7α-thiol-γ-lacton-7-acetat, 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-en-21-carbonsäure-γ-lacton
• Empirische Formel (Hill-System): C₂₄H₃₂O₄S
• CAS-Nummer: 52-01-7
• Molekulargewicht: 416.57
• MDL-Nummer: MFCD00082250
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP BP306; traceable to Ph. Eur. S1200000; traceable to USP 1619006
• API-Familie: spironolactone
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 200 mg
• mp (Schmelzpunkt): 207-208 °C (lit.)
• Anwendung(en): pharmaceutical
• Lagertemp.: 2-30°C
• SMILES String: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13
• InChI: 1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
• InChIKey: LXMSZDCAJNLERA-ZHYRCANASA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Spironolacton ist ein kompetitiver Aldosteron-Rezeptor-Antagonist. Wird als Kaliumsparendes Diuretikum verwendet.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H351,H360FD,H373
• P-Sätze: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Carc. 2 - Repr. 1B - STOT RE 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable