PHR1569

Levocarnitin

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): L-Carnitin Inneres Salz, (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrat, Vitamin B_T
• Lineare Formel: (CH₃)₃N⁺CH₂CH(OH)CH₂COO^-
• CAS-Nummer: 541-15-1
• Molekulargewicht: 161.20
• Beilstein: 4292315
• EG-Nummer: 208-768-0
• MDL-Nummer: MFCD00038747
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823478
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. L0399900; traceable to USP 1359903
• API-Familie: levocarnitine
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• mp (Schmelzpunkt): 197-212 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: C[N+](C)(C)C[C@H](O)CC([O-])=O
• InChI: 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
• InChIKey: PHIQHXFUZVPYII-ZCFIWIBFSA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Carnitin ist ein quaternäres Amin, das natürlich in den meisten Säugetiergeweben vorkommt. Es ist in relativ hoher Konzentration im Skelettmuskel und im Herzen vorhanden, wo es an der Regulierung des Energiestoffwechsels beteiligt ist. Es verschiebt den Glucosestoffwechsel von der Glycolyse zur Glycogen-Speicherung und verbessert den Transport von langkettigen Fettsäuren in die Mitochondrien, wo sie zur Energiegewinnung oxidiert werden.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable