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Merck

PHR1118

Supelco

Propylgallat

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

3,4,5-Trihydroxybenzoesäure-propylester, Propyl-gallat, Tenox PG

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About This Item

Lineare Formel:
3,4,5-(HO)3C6H2CO2CH2CH2CH3
CAS-Nummer:
Molekulargewicht:
212.20
Beilstein:
1877976
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
E-Nummer:
E310
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to Ph. Eur. P3640000
traceable to USP 1576800

API-Familie

propyl gallate

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

146-149 °C (lit.)

Anwendung(en)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CCCOC(=O)c1cc(O)c(O)c(O)c1

InChI

1S/C10H12O5/c1-2-3-15-10(14)6-4-7(11)9(13)8(12)5-6/h4-5,11-13H,2-3H2,1H3

InChIKey

ZTHYODDOHIVTJV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propyl gallate is a synthetic phenolic antioxidant (SPA) utilized in food additives to inhibit or regulate the lipid oxidation. SPAs are cost-effective, largely available and highly efficient in comparison to their natural counterparts.

Anwendung

Propyl gallate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and fatty liquids by chromatography and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Rekonstituierung

Bereiten Sie eine 0.1 M Lösung in Glycerin:PBS (9:1).

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA8981 in the slot below. This is an example certificate only and may not be the lot that you receive.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

368.6 °F - closed cup

Flammpunkt (°C)

187 °C - closed cup


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Method validation and measurement uncertainty for the simultaneous determination of synthetic phenolic antioxidants in edible oils commonly consumed in Korea
Kim JM, et al.
Food Chemistry, 213(6), 19-25 (2016)
Determination of some antioxidants by derivative spectrophotometric method and high-performance liquid chromatography
Ivanovic D, et al.
Analytical Letters, 23(6), 1123-1137 (1990)
Detection and quantification of low-molecular-weight aldehydes in pharmaceutical excipients by headspace gas chromatography
Li Z, et al.
Journal of Chromatography A, 1104(1-2), 1-10 (2006)
Ching-Hsein Chen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(2), 494-501 (2010-11-30)
Propyl gallate (PG) is a synthetic antioxidant that has been used in processed food and medicinal preparations. The anti-cancer effect of PG in leukemia is unclear. In the present study, we demonstrate that PG reduced cell viability in THP-1, Jurkat
Yasunobu Kawano et al.
Resuscitation, 83(2), 249-252 (2011-08-02)
The present study was conducted to assess the effects of intraperitoneal administration of n-propyl gallate (PG) on hippocampal neuronal survival after forebrain ischemia. Forty male Sprague-Dawley rats were randomly assigned to one of 6 groups. Animals in the PG-I-10, PG-I-8

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