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Merck

P3750000

Propyphenazon

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

4-Isopropylantipyrin, 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-on, 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-on, Isopropylphenazon, Propyphenazon

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About This Item

Empirische Formel (Hill-System):
C14H18N2O
CAS-Nummer:
Molekulargewicht:
230.31
Beilstein:
204533
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

propyphenazone 

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2

InChI

1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3

InChIKey

PXWLVJLKJGVOKE-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Propyphenazone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Deniz Emre et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 847(2), 126-132 (2006-10-19)
A new micellar electrokinetic capillary chromatographic method has been developed to analyze the pharmaceutical preparations containing ternary combination of paracetamol (PAR), caffeine (CAF) and propyphenazone (PRO). Best results were obtained by using 20mM pH 9.0 borate buffer containing 30mM sodiumdodecylsulphate
Andreas Lemmerer et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(48), 13445-13460 (2011-11-15)
A co-crystal of two polymorphic active pharmaceutical ingredients (APIs), first reported and patented in 1937, has been prepared and thoroughly characterised, including crystal structure analysis. The existence of four crystal forms of one of the APIs, the sedative and hypnotic
Sebastian Zühlke et al.
Journal of chromatography. A, 1050(2), 201-209 (2004-10-29)
A new analytical method applying in situ derivatization was developed to enable the extraction of polar drug metabolites from water samples by solid-phase extraction (SPE). An additional derivatization by silylation was used to enhance the sensitivity of analyte detection by
Acute inferior myocardial infarction with low atrial rhythm due to propyphenazone: Kounis syndrome.
Ahmet Akyel et al.
International journal of cardiology, 148(3), 352-353 (2010-06-15)
Rosario Rodil et al.
Water research, 46(7), 2457-2468 (2012-03-03)
Chlorination is one of the most popular disinfection steps for water treatment in Europe. However, chlorine can react with pharmaceuticals and other micropollutants leading to either their elimination or by-products being formed. These by-products are frequently not identified and therefore

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