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H0800000

Homatropin -hydrobromid

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

DL-Homatropin -hydrobromid

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About This Item

Empirische Formel (Hill-System):
C16H21NO3 · HBr
CAS-Nummer:
Molekulargewicht:
356.25
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

homatropine

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

214-217 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

InChIKey

DWSGTFTVBLXELC-UHFFFAOYSA-N

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Allgemeine Beschreibung

Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Brian M Thome et al.
Journal of chromatography. A, 1138(1-2), 291-300 (2006-11-14)
Over the past decade the moving bed process has become a commonly used tool for the continuous separation of chiral compounds, and its recent application to electrophoretic separations allows the technique to be used as a model system for moving
Homatropine and psychosis in Weill-Marchesani syndrome.
Anjaiah Madugula et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 45(7), 769-770 (2006-07-13)
Determination of homatropine hydrobromide in eye drops by second-order derivative spectroscopy.
Leung C P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 9(2), 195-198 (1991)
Bhavna Chawla et al.
International ophthalmology, 29(1), 53-55 (2007-11-17)
To report a case of peripheral ulcerative keratitis (PUK) and scleritis, along with bilateral optic nerve infiltration as an initial presentation of acute lymphocytic leukemia (ALL) in an adult. Observational case report. A 24-year-old patient presented with complaints of pain
Robert Meek et al.
Emergency medicine Australasia : EMA, 22(6), 507-513 (2010-12-15)
To compare the change in visual analogue scale (VAS) pain ratings over 24 h following mechanical corneal abrasion between patients receiving sixth hourly drops of either 5% homatropine or placebo. A triple blind randomized controlled trial was conducted on a

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