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D1750000

Diflunisal

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

2′,4′-Difluor-4-hydroxy-[1,1′-biphenyl]-3-carbonsäure, 5-(2,4-Difluorphenyl)-salicylsäure

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About This Item

Empirische Formel (Hill-System):
C13H8F2O3
CAS-Nummer:
22494-42-4
Molekulargewicht:
250.20
MDL-Nummer:
MFCD00057834
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329798707
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

diflunisal

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

FC1=CC(F)=CC=C1C2=CC(C(O)=O)=C(O)C=C2

InChI

1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)

InChIKey

HUPFGZXOMWLGNK-UHFFFAOYSA-N

Angaben zum Gen

human ... PTGS1(5742) , PTGS2(5743)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Diflunisal EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Exclamation markHealth hazard
GHS07,GHS08

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

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Die Dokumentenbibliothek aufrufen

Jack O Wasey et al.
The Cochrane database of systematic reviews, (4)(4), CD007440-CD007440 (2010-04-16)
Diflunisal is a long-acting non-steroidal anti-inflammatory drug (NSAID) most commonly used to treat acute postoperative pain or chronic joint pain from osteoarthritis and rheumatoid arthritis. This review analyses the effectiveness and harm of different doses of diflunisal in the context
G M Lawton et al.
Australian dental journal, 38(4), 265-271 (1993-08-01)
Diflunisal is frequently used for management of postoperative dental pain as it has some advantages over other commonly used non-steroidal anti-inflammatory drugs including improved analgesia, a prolonged duration of action lasting up to 12 hours, and a low incidence of
R N Brogden et al.
Drugs, 19(2), 84-106 (1980-02-01)
Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. It has been studied in osteoarthritis, pain resulting from musculoskeketal sprains and strains and from minor surgery and cancer. The duration of its analgesic effect is longer than that
M W Rich et al.
Chest, 111(6), 1767-1769 (1997-06-01)
Drug-induced pneumonitis is an uncommon complication of nonsteroidal anti-inflammatory drug administration. Herein is the first reported case of pneumonitis resulting from diflunisal therapy. The patient demonstrated clinical and biopsy evidence of systemic vasculitis. She responded dramatically to administration of systemic
R O Davies
Pharmacotherapy, 3(2 Pt 2), 9S-22S (1983-03-01)
Diflunisal is a new salicylic acid derivative identified after a search for a compound with improved potency, enhanced gastrointestinal tolerance relative to its antiinflammatory activity, and a longer duration of action than that of aspirin. Animal and clinical studies have
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