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Merck

46166

Supelco

Dexamethason-21-Acetat

VETRANAL®, analytical standard

Synonym(e):

9α-Fluor-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion-21-acetat, 9α-Fluor-16α-methyl-prednisolon-21-acetat, Prednisolon F-acetat

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About This Item

Empirische Formel (Hill-System):
C24H31FO6
CAS-Nummer:
Molekulargewicht:
434.50
Beilstein:
2342608
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

clinical

Format

neat

Lagertemp.

2-8°C

SMILES String

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChIKey

AKUJBENLRBOFTD-RPRRAYFGSA-N

Angaben zum Gen

human ... NR3C1(2908)

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Die Dokumentenbibliothek aufrufen

Xuefan Xu et al.
Drug delivery, 18(7), 485-492 (2011-06-23)
This work studied the intravenous injection formulation of nanostructured lipid carriers (NLCs) loaded with dexamethasone acetate (DA), a poorly water-soluble drug. The goal of this study was to design nanoparticles which could improve therapeutic efficacy of DA on inflammations. Based
Kam-Lun Ellis Hon et al.
The Journal of dermatological treatment, 19(4), 241-245 (2008-07-17)
Many parents purchase topical applications without knowing what they contain, and apply them liberally to their children with dermatological disorders. In one such case, an infant developed fever, diarrhea and a small ulcer near the right labia majora which was
T Lifshitz et al.
Ophthalmic surgery and lasers, 32(2), 159-161 (2001-04-13)
Retrocorneal membranes after penetrating keratoplasty (PKP) is a well known complications, resulting from unintentional retention of the host Descemet's membrane (DM), or donor DM detachment. We describe for the first time the formation of a retrocorneal inflammatory membrane that mimics
Sandra A L Moura et al.
Journal of pharmaceutical sciences, 100(7), 2886-2895 (2011-02-02)
Implants are defined as controlled sustained release delivery systems of therapeutic agents incorporated or dispersed into a polymeric carrier. These systems can be implanted in specific organs and delivered by the therapeutic agents at the target site to treat various
S L Fialho et al.
Current eye research, 31(6), 525-534 (2006-06-14)
The treatment of vitreoretinal diseases is limited and, nowadays, new drug delivery approaches have been reported in order to increase drug bioavailability. The objective of the current study was to determine the pharmacokinetic profile of a biodegradable dexamethasone acetate implant

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