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Merck

222461

Sigma-Aldrich

Murexid

ACS reagent

Synonym(e):

5,5′-Nitrilodibarbitursäure Monoammoniumsalz, Ammoniumpurpurat

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About This Item

Empirische Formel (Hill-System):
C8H8N6O6
CAS-Nummer:
Molekulargewicht:
284.19
Farbindexnummer:
56085
Beilstein:
3831445
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47

Qualität

ACS reagent

Qualitätsniveau

Form

powder

Methode(n)

titration: suitable

mp (Schmelzpunkt)

>300 °C (lit.)

λmax

525 nm

Eignung

passes test for complexometric indicator

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

N.OC1=C(\N=C2\C(=O)NC(=O)NC2=O)C(=O)NC(=O)N1

InChI

1S/C8H5N5O6.H3N/c14-3-1(4(15)11-7(18)10-3)9-2-5(16)12-8(19)13-6(2)17;/h(H2,10,11,14,15,18)(H3,12,13,16,17,19);1H3

InChIKey

LJYRLGOJYKPILZ-UHFFFAOYSA-N

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Allgemeine Beschreibung

Murexide is the ammonium salt of purpuric acid that appears as a slightly reddish-purple powder and is soluble in water. It is mainly used as an indicator for complexometric titrations to measure water hardness and as a colorant/pigment in the dye industry.

Anwendung

Murexide is used for the histochemical staining of calcium in the skeleton. It is suitable for staining the hemijaws for dental caries scoring.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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F D Coffman et al.
Biochemistry, 27(16), 6179-6187 (1988-08-09)
An insulin hexamer containing one B10-bound Co(III) ion and one unoccupied B10 site has been synthesized. The properties of the monosubstituted hexamer show that occupancy of only one B10 site by Co3+ is sufficient to stabilize the hexameric form under
A Hirota et al.
The Journal of general physiology, 94(4), 597-631 (1989-10-01)
Two new Ca indicators, purpurate-3,3'diacetic acid (PDAA) and 1,1'-dimethylpurpurate-3,3'diacetic acid (DMPDAA), were synthesized and used to measure Ca transients in frog cut muscle fibers. These indicators are analogues of the purpurate components of murexide and tetramethylmurexide, in which two acetate
H Gusman et al.
Biochimica et biophysica acta, 1545(1-2), 86-95 (2001-05-09)
Histatins are small histidine-rich salivary polypeptides which exhibit antimicrobial activity against Candida albicans. This antimicrobial activity has been ascribed in part to a high content of basic amino acids. However, unlike most other antimicrobial proteins histatins have a high content
Cédric R H Lamboley et al.
Cell calcium, 50(6), 530-547 (2011-11-01)
One aim of this article was to determine the resting concentration of free Ca(2+) in the sarcoplasmic reticulum (SR) of frog cut skeletal muscle fibers ([Ca(2+)](SR,R)) using the calcium absorbance indicator dye tetramethylmurexide (TMX). Another was to determine the ratio
J Maylie et al.
The Journal of general physiology, 89(1), 145-176 (1987-01-01)
The Ca indicator tetramethylmurexide was introduced into cut fibers, mounted in a double-Vaseline-gap chamber, by diffusion from the end-pool solutions. The indicator diffused rapidly to the central region of a fiber where optical recording was done and, if removed, diffused

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