10602361001

Plasmin, human

from human plasma

• Synonym(e): Plasmin
• EC-Nummer: 3.4.21.7 (BRENDA, IUBMB)
• UNSPSC-Code: 12352204

Eigenschaften

• Biologische Quelle: human plasma
• Qualitätsniveau: 100
• Assay: 95% (electrophoresis)
• Form: suspension
• Spezifische Aktivität: ~8 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
• Mol-Gew.: M_r ~85 kDa
• Verpackung: pkg of 0.5 mL (5 U)
• Hersteller/Markenname: Roche
• Optimaler pH-Wert: 8.9
• Versandbedingung: wet ice

Beschreibung

Allgemeine Beschreibung

Inhibitors: DFP, PMSF, TLCK, leupeptin, aprotinin, soybean trypsin inhibitor, α₁-antitrypsin, α₂-macroglobulin, anti-thrombin III heparin, APMSF, and α₂-antiplasmin

Fibrinolysin

Spezifität

Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.

Anwendung

Human plasmin has been used as an oligopeptide substrate in peptidase inhibition assays.

Biochem./physiol. Wirkung

Plasmin is a direct acting fibrinolytic enzyme present in blood. Its activity is independent of plasminogen presence during fibrinolysis. Plasmin is rapidly and irreversibly inhibited by α-2 antiplasmin.

Physikalische Form

Suspension in 3.2 M ammonium sulfate solution

Angaben zur Herstellung

Stabilizers: Human plasmin does not contain stabilizers.
Storage conditions (working solution): 2 to 8 °C
Diluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended.

Lagerung und Haltbarkeit

Store at 2 to 8 °C. (Recommended form for storage is ammonium sulfate suspension 3.2 M, pH 8.6.)

Sonstige Hinweise

For life science research only. Not for use in diagnostic procedures.

Haftungsausschluss

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 + P310 - P501
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available