MSCRMAG-42K

MILLIPLEX^® Mouse Soluble Cytokine Receptor Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

• UNSPSC-Code: 12161503
• eCl@ss: 32161000

Eigenschaften

• Qualitätsniveau: 200
• Speziesreaktivität: mouse
• Hersteller/Markenname: Milliplex^®
• assay range: accuracy: 89-98%; standard curve range: 12.2-50,000 pg/mL; (sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sTNFRII); standard curve range: 24.4-100,000 pg/mL; (sCD30, sgp130, sIL-6R, sRAGE, sVEGFR1, sVEGFR2, sVEGFR3); standard curve range: 4.9-20,000 pg/mL; (sTNFRI)
• Methode(n): multiplexing: suitable
• Nachweisverfahren: fluorometric (Luminex xMAP)
• Versandbedingung: wet ice

Beschreibung

Allgemeine Beschreibung

Cytokine receptors constitute an integral part of the cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane-bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.

The MILLIPLEX^® Mouse Soluble Cytokine Receptor Panel contains 13 metastasis biomarkers that have also been identified in a variety of therapeutic areas. Coupled with the Luminex^® xMAP^® platform in bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity.

Panel Type: Cytokines/Chemokines

Anwendung

• Analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4)
• Recommended Sample type: serum, plasma and cell culture
• Recommended Sample dilution: 1:5 diluted serum and plasma
• Assay Run Time: Overnight
• Research Category: Inflammation & Immunology

Leistungsmerkmale und Vorteile

Design your multiplex kit by choosing available analytes within this panel.

Verpackung

Everything you need in a single kit.

Sonstige Hinweise

Please contact Technical Service for linearity of dilution.

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Rechtliche Hinweise

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332 - H315 - H317 - H319 - H335 - H411
• P-Sätze: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3