MABN314

Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody

clone 3D2.1, from mouse

• Synonym(e): Gamma-synuclein, Breast cancer-specific gene 1 protein, Persyn, Synoretin, SR
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 3D2.1, monoclonal
• Speziesreaktivität: human
• Methode(n): western blot: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NP_003078
• UniProt-Hinterlegungsnummer: O76070
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SNCG(6623)

Beschreibung

Allgemeine Beschreibung

Gamma-synuclein is one four proteins in the synuclein family, Gamma-synuclein appears to play a role in neurofilament network integrity and interaction. Gamma synuclein is important for axonal architecture and maintenance and the protein interacts with both the MAPK and ELK-1 signaling networks. Gamma synuclein is a cytoplasmically associated protein that is also strongly associated with cytoskeletal elements. During cell division, gamma synuclein is associated with the poles of the spindle and interruption causes defects in cytokinesis. Gamma synuclein is highly expressed in the brain but can also be found expressed in the heart, skeletal muscle, colon, and gonads. Gamma synuclein is also expressed in many invasive cancers.

Immunogen

GST-tagged recombinant protein corresponding to human Gamma-synuclein (SNCG).

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Entwicklungsabhängige Signalübertragung

This Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody is validated for use in Western Blotting for the detection of Gamma-synuclein (SNCG).

Qualität

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Gamma-synuclein (SNCG) in 10 µg of human cortex tissue lysate.

Zielbeschreibung

~15 kDa observed

Physikalische Form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Sonstige Hinweise

Concentration: Please refer to lot specific datasheet.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable