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Key Documents

MAB3414

Sigma-Aldrich

Anti-Cytokeratin 8 Antibody, clone 4.1.18

clone 4.1.18, Chemicon®, from mouse

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

4.1.18, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_002273.2

UniProt-Hinterlegungsnummer

P05787

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... KRT8(3856)

Spezifität

The antibody reacts with human cytokeratin 8. There is no cross reactivity with human cytokeratin No. 7, 17, 18, or 19. Anti-cytokeratin No. 8 decorates single epithelia in stomach, colon, and small intestine, gall bladder, liver (bile ducts and hepatocytes) as well as pancreatic ducts and mammary gland ducts.

Immunogen

Cytoskeletal preparation of MCF-7 cells.

Anwendung

This Anti-Cytokeratin 8 Antibody, clone 4.1.18 is validated for use in WB, IC, IH, IH(P) for the detection of Cytokeratin 8.
Western blot Immunocytochemistry Immunohistochemistry: Frozen sections, acetone fixed (5-10 μg/mL)

Paraffin sections, after trypsin treatment (5-20 μg/mL)

Optimal-working dilutions must be determined by end user.

Verlinkung

Replaces: 04-588

Physikalische Form

Format: Purified
Lyophilized from 0.02 M Phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Patterns of expression and organization of cytokeratin intermediate filaments.
Quinlan, R A, et al.
Annals of the New York Academy of Sciences, 455, 282-306 (1985)
Cristián Vela Hinojosa et al.
PloS one, 8(9), e75062-e75062 (2013-10-03)
The mammary gland has long drawn the attention of the scientific community due to the limited knowledge of some fundamental aspects involved in the control of its function. Myotis velifer, a microchiropteran species, provides an interesting model to study some
Sinyoung Kim et al.
International journal of molecular medicine, 27(5), 701-706 (2011-02-25)
Although recent studies have demonstrated the in vitro hepatic differentiation potential of mesenchymal stem cells (MSCs), the evidence supporting the in vivo engraftment of MSCs, hepatic differentiation and improvement of hepatic function is still lacking. We investigated in vivo hepatic
Yan Zhuang et al.
Molecular carcinogenesis, 54(12), 1656-1667 (2014-10-21)
Epigenetic regulation of gene expression is critical to phenotypic maintenance and transition of human breast cancer cells. HOX antisense intergenic RNA (HOTAIR) is a long intergenic non-coding RNA that epigenetically represses gene expression via recruitment of enhancer of zeste homolog
The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells.
R Moll et al.
Cell, 31(1), 11-24 (1982-11-01)

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