GF309

NT-4 Protein, Human Recombinant Animal Free

The Neurotrophin-4 protein (or NT-4 protein), also known as NT-5 protein, is a member of the NGF family of neuronal & epithelial growth factors.

• Synonym(e): NT4, Neurotrophin 4, Neurotrophin 4/5, NT4/5
• UNSPSC-Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: >98% (SDS-PAGE and HPLC)
• Verunreinigungen: <0.1 μg/mg protein endotoxin (<1EU/μg)
• NCBI-Hinterlegungsnummer: NM_006179.3
• UniProt-Hinterlegungsnummer: P34130
• Versandbedingung: dry ice

Beschreibung

Allgemeine Beschreibung

Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).

Spezifität

Cross Reactivty
Mouse, Rat

Qualität

Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.

Physikalische Form

Recombinant animal free human NT-4 is manufactured using all non-animal reagents

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable