8.08388

1,2,4-Triazole

for synthesis

• Synonym(e): 1,2,4-Triazole
• Empirische Formel (Hill-System): C₂H₃N₃
• CAS-Nummer: 288-88-0
• Molekulargewicht: 69.07
• MDL-Nummer: MFCD00005228
• UNSPSC-Code: 12352005
• EG-Index-Nummer: 206-022-9

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.0% (GC)
• Form: solid
• Wirksamkeit: 1650 mg/kg LD₅₀, oral (Rat); 3129-4200 mg/kg LD₅₀, skin (Rabbit)
• pH-Wert: 8 (20 °C, 10 g/L in H₂O)
• bp: 259-261 °C/1013 hPa
• mp (Schmelzpunkt): 119-122 °C
• Dichte: 1.15 g/cm³ at 130 °C
• Schüttdichte: 550 kg/m³
• Lagertemp.: 2-30°C
• InChI: 1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)
• InChIKey: NSPMIYGKQJPBQR-UHFFFAOYSA-N

Beschreibung

Anwendung

• Chemistry of 1, 2, 4-triazole: a review article: This comprehensive review explores the broad applications of 1,2,4-triazole in pharmaceuticals, demonstrating its role in enhancing antibacterial, antifungal, and antioxidant properties (Shneine et al., 2016).
• Combination of 1, 2, 3-triazole and 1, 2, 4-triazole frameworks for new high-energy and low-sensitivity compounds: Discusses the synthesis of energetic materials combining 1,2,4-triazole with other high-energy frameworks, aiming to enhance performance and safety (Yao et al., 2021).
• 1, 3, 4-Oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4-triazole derivatives as potential antibacterial agents: Examines derivatives of 1,2,4-triazole for potential use in antibacterial treatments, reflecting on their pharmacological importance (Othman et al., 2019).
• Recent developments on 1, 2, 4-triazole nucleus in anticancer compounds: a review: Reviews the incorporation of the 1,2,4-triazole nucleus in various anticancer compounds, showcasing the therapeutic potential of this moiety (Kaur et al., 2016).

Hinweis zur Analyse

Gehalt (GC, Fl.%): ≥ 98.0 % (a/a)
Schmelzbereich (unterer Wert): ≥ 117 °C
Schmelzbereich (oberer Wert): ≤ 121 °C
Identität (IR): entspricht

Sicherheitshinweise

• Piktogramme: GHS07,GHS08
• Signalwort: Danger
• H-Sätze: H302 - H319 - H360FD
• P-Sätze: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): 338.0 °F
• Flammpunkt (°C): 170 °C