561306

P-Selectin, Human, Recombinant, CHO Cells

• Synonym(e): CD62P, GMP-140, LECAM-3, PADGEM
• UNSPSC-Code: 12352202
• NACRES: NA.75

Eigenschaften

• Rekombinant: expressed in CHO cells
• Qualitätsniveau: 100
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Verunreinigungen: <1.5 EU/μg Endotoxins (EU/μg of P-Selectin)
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.

Biochem./physiol. Wirkung

Shown to bind to P-selectin ligands on U937 cells.

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

Lyophilized from Dulbecco’s D-PBS (containing calcium and magnesium), 1% sorbitol.

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute at 1 mg/ml in sterile H₂O.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2