5.08160

DPDPE

• Synonym(e): DPDPE, δ Opioid Receptor Agonist, DPDPE
• Empirische Formel (Hill-System): C₃₀H₃₉N₅O₇S₂
• CAS-Nummer: 88373-73-3
• Molekulargewicht: 645.79
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥99% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: off-white
• Löslichkeit: water: 1 mg/mL
• Lagertemp.: −20°C
• InChI: 1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1
• InChIKey: MCMMCRYPQBNCPH-WMIMKTLMSA-N

Beschreibung

Allgemeine Beschreibung

A potent agonist selective for δ opioid receptor (EC₅₀ = 5.2 nM). Exhibits anti-convulsant effects in vivo in rats, also used in nociceptive studies.

Biochem./physiol. Wirkung

Primary Target
δ opioid receptor

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Chen, C., 1997. J. Pharmacol. Exp. Ther.283, 1151.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable