239785

Cyclophosphamide Monohydrate

≥98% (HPLC), solid, anti-neoplastic agent, Calbiochem^®

• Synonym(e): Cyclophosphamide Monohydrate, N,N- bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA, N,N-bis(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide Monohydrate, CPA
• Empirische Formel (Hill-System): C₇H₁₅Cl₂N₂O₂P · xH₂O
• CAS-Nummer: 6055-19-2
• Molekulargewicht: 261.09 (anhydrous basis)
• MDL-Nummer: MFCD00149395
• UNSPSC-Code: 51112507
• NACRES: NA.77

Eigenschaften

• product name: Cyclophosphamide Monohydrate, A widely used anti-neoplastic agent that also displays immunosuppressant properties.
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Farbe: white
• Löslichkeit: water: 30 mg/mL
• Versandbedingung: ambient
• Lagertemp.: 2-8°C
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChIKey: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

A widely used anti-neoplastic agent that also displays immunosuppressant properties. Induces apoptotic cell death in rat thymus through the Fas/Fas ligand pathway.

A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Fas/Fas ligand pathway

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

Rekonstituierung

Solutions should be prepared fresh on the day of use.

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Wang, G.J., and Cai, L. 1999. Mutat. Res.427, 125.
Lee, J.H., et al. 1997. Korean J. Med. Sci. 12, 185.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H340,H350,H360FD
• P-Sätze: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3