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Merck
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Dokumente

05-882

Sigma-Aldrich

Anti-Parkin Antibody, clone PRK8

ascites fluid, clone PRK8, Upstate®

Synonym(e):

Anti-AR-JP, Anti-LPRS2, Anti-PARK2, Anti-PDJ

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

PRK8, monoclonal

Speziesreaktivität

human, mouse

Hersteller/Markenname

Upstate®

Methode(n)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI-Hinterlegungsnummer

NM_004562

UniProt-Hinterlegungsnummer

O60260

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PARK2(5071)

Spezifität

Parkin

Immunogen

Full length recombinant human Parkin. Epitope has been mapped to the second ring domain (aa 399-465)

Anwendung

Anti-Parkin Antibody, clone PRK8 detects level of Parkin & has been published & validated for use in IP, WB, IC, IH.

Qualität

routinely evaluated by immunoblot on RIPA lysates from HEK293 cells

Zielbeschreibung

52kDa May be observed as a doublet at 52 and 46kDa

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Are ubiquitination pathways central to Parkinson's disease?
Giasson, Benoit I and Lee, Virginia M-Y
Cell, 114, 1-8 (2003)
Molecular pathways of neurodegeneration in Parkinson's disease.
Dawson, Ted M and Dawson, Valina L
Science (New York, N.Y.), 302, 819-822 (2003)
Genotype-phenotype correlation: familial Parkinson disease.
Mori, Hideo, et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 23, 90-94 (2003)
Nobutaka Hattori et al.
Lancet (London, England), 364(9435), 722-724 (2004-08-25)
The cause and pathogenesis of Parkinson's disease remain unknown; mitochondrial dysfunction, oxidative damage, environmental factors, and genetic predisposition might all be involved. Identification of the causative genes for familial Parkinson's diseases allow study of the pathogenesis of the disease at
Keiji Tanaka et al.
Biochimica et biophysica acta, 1695(1-3), 235-247 (2004-12-02)
The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control
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