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Merck

T-018

Supelco

(−)-11-nor-9-Carboxy-Δ9-THC -Lösung

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C21H28O4
CAS-Nummer:
Molekulargewicht:
344.44
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

Konzentration

100 μg/mL in methanol

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Eignung

suitable for immunoassay

Anwendung(en)

cannabis testing
forensics and toxicology

Format

single component solution

Lagertemp.

2-8°C

SMILES String

CCCCCC(C=C1O)=CC2=C1[C@@]3([H])[C@@](C(C)(C)O2)([H])CCC(C(O)=O)=C3

InChI

1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)/t15-,16-/m1/s1

InChIKey

YOVRGSHRZRJTLZ-HZPDHXFCSA-N

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Allgemeine Beschreibung

An analytical reference standard suitable in cannabinoid testing, clinical toxicology, forensic analysis, or urine drug testing by LC-MS/MS or GC/MS. Also known as THC acid, 11-nor-9-Carboxy-Δ9-THC is the main secondary metabolite of THC found in urine or blood of cannabis users.

Anwendung

  • Advanced analytical method development: A study by DeGregorio et al. introduces a Liquid Chromatography High-Resolution Mass Spectrometry (LC-HRMS) bioanalytical method for quantifying cannabinoids, including (−)-11-nor-9-Carboxy-Δ?-THC, in whole blood. This method is pivotal for determining recent cannabis use, offering significant advancements in forensic toxicology and drug testing (DeGregorio et al., 2020).
  • Cannabinoid serum analysis: Gottardo et al. present the first application of atmospheric-pressure chemical ionization gas chromatography tandem mass spectrometry for the determination of cannabinoids in serum. This groundbreaking technique enhances the detection and quantification of cannabinoids, including (−)-11-nor-9-Carboxy-Δ?-THC, facilitating deeper insights into cannabinoid pharmacokinetics and toxicology (Gottardo et al., 2019).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Yannick Lecompte et al.
Journal of analytical toxicology, 36(8), 569-574 (2012-08-31)
The guidelines for screening of urinary cannabinoids require that all specimens testing positive should be confirmed by gas chromatography-mass spectrometry at a confirmatory test cutoff value of 15 ng/mL of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH). To assess the impact of lowering the confirmatory
Vanessa de M Prata et al.
Analytical and bioanalytical chemistry, 403(2), 625-632 (2012-03-01)
A new procedure is described for the derivatization by silylation of 11-nor-Δ(9)-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) present in urine, followed by analysis using gas chromatography-tandem mass spectrometry. A conventional procedure for derivatization of the analyte was evaluated using two types of experimental
Iria González-Mariño et al.
Analytical chemistry, 84(3), 1708-1717 (2011-12-22)
For the first time, a mixed-mode solid-phase extraction with fractionation of basic analytes from neutral and acidic species during cartridge elution and liquid chromatography-quadrupole-time-of-flight mass spectrometry (LC-QTOF-MS) was combined for the quantitative determination of 24 illicit drugs and metabolites in
Gabriele Zanchetti et al.
Journal of mass spectrometry : JMS, 47(1), 124-130 (2012-01-28)
A method for the rapid and robust confirmation of 11-nor-∆9-tetrahydrocannabinol-9-carboxylic acid (THCA) in urine involving basic hydrolysis with NaOH and direct injection of the hydrolysate in a column-switching LC-MS-MS system was developed and validated. THCA-d3 was used as internal standard.
Cynthia Coulter et al.
Journal of analytical toxicology, 36(6), 413-417 (2012-04-26)
This paper describes the determination of tetrahydrocannabinol (THC) and its metabolite, 11-nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in oral fluid using solid-phase extraction and liquid chromatography with tandem mass spectral detection (LC-MS-MS) and its application to proficiency specimens. The method employs collection of

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