999989C

18:1 Diether PC

1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine, chloroform

• Synonym(e): Dioctadecenyl PC
• Empirische Formel (Hill-System): C₄₄H₈₈NO₆P
• CAS-Nummer: 105370-99-8
• Molekulargewicht: 758.15
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Form: liquid
• Verpackung: pkg of 1 × 1 mL (999989C-10mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 999989C
• Konzentration: 10 mg/mL (999989C-10mg)
• Lipid-Typ: phospholipids; cardiolipins
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)=O

Beschreibung

Allgemeine Beschreibung

18:1 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Anwendung

18:1 Diether PC or 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine might be used:

• to prepare proteoliposomes to investigate the effects of ceramide and ceramide phosphate/ for the determination of phospholipase A activity of lecithin-cholesterol acyltransferase (LCAT) in the ether matrix
• to prepare lipid bilayer membrane to study the influence of glutamic acid residues and pH on the properties of transmembrane helices
• in large unilamellar vesicles (LUVs) to explore the differential interaction of pH (low) insertion peptide (pHLIP) with it by utilizing fluorescence and circular dichroism (CD) spectroscopic approaches

Biochem./physiol. Wirkung

Lipids prepared using 18:1 Diether PC (phosphocholine), are found to be more stable than the natural ester lipids under alkaline conditions.

Verpackung

5 mL Clear Glass Sealed Ampule (999989C-10mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• P-Sätze: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Zielorgane: Central nervous system, Liver,Kidney
• WGK: WGK 3