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810258E

Avanti

C11 TopFluor™ GM3

Avanti Research™ - A Croda Brand 810258E, ethanol solution

Synonym(e):

C11 TopFluor GM3 Ganglioside (ammonium salt)

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About This Item

Empirische Formel (Hill-System):
C65H110BF2N5O21
CAS-Nummer:
2260795-48-8
Molekulargewicht:
1346.40
MDL-Nummer:
MFCD00066515
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

ethanol solution

Verpackung

pkg of 1 × 1 mL (810258E-100ug)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 810258E

Konzentration

0.1 mg/mL (810258E-100ug)

Versandbedingung

dry ice

Lagertemp.

−20°C

Verwandte Kategorien

Allgemeine Beschreibung

C11 TopFluor™ GM3 is a fluorescent analog of ganglioside GM3 (Siaa2-3Galb1-4Glcb1-1Cer).

Anwendung

C11 TopFluor™ GM3 has been used to visualize GM3 present in UGCG-KO1.3 cells by immunofluorescence microscopy.

Biochem./physiol. Wirkung

Gangliosides function as modulators in regulating various receptor functions, involved in transmembrane signaling. GM3 plays an important role as a metabolic precursor for the formation of more complex gangliosides. It comprises between 80% and 90% of total ganglioside content in liver and adipose tissue, respectively. Additionally, GM3 is known to promote the subcellular redistribution of major caveolin enriched microdomain (CEM) components coordinating signal transduction. The increased levels of ganglioside GM3 in serum is reported in hyperlipidaemic, hyperglycaemic and type 2 diabetic patients.

Verpackung

5 mL Amber Glass Screw Cap Vial (810258E-100ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

H-Sätze

H225,H319

Gefahreneinstufungen

Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

55.4 °F - closed cup

Flammpunkt (°C)

13.0 °C - closed cup

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Analysenzertifikate (COA)

Lot/Batch Number

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Seiichi Tagami et al.
The Journal of biological chemistry, 277(5), 3085-3092 (2001-11-15)
Gangliosides are known as modulators of transmembrane signaling by regulating various receptor functions. We have found that insulin resistance induced by tumor necrosis factor-alpha (TNF-alpha) in 3T3-L1 adipocytes was accompanied by increased GM3 ganglioside expression caused by elevating GM3 synthase
Anshuman Das et al.
Nature microbiology, 5(9), 1069-1078 (2020-05-27)
The Picornaviridae are a diverse family of positive-strand RNA viruses that includes numerous human and veterinary pathogens1. Among these, hepatitis A virus (HAV), a common cause of acute hepatitis in humans, is unique in that it is hepatotropic and is

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