810130P
Avanti
16:0-06:0 NBD PC
Avanti Research™ - A Croda Brand 810130P, powder
Synonym(e):
1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
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About This Item
Empfohlene Produkte
Assay
>99% (TLC)
Form
powder
Verpackung
pkg of 1 × 1 mg (810130P-1mg)
pkg of 5 × 1 mg (810130P-5mg)
Hersteller/Markenname
Avanti Research™ - A Croda Brand 810130P
Versandbedingung
dry ice
Lagertemp.
−20°C
Verwandte Kategorien
Allgemeine Beschreibung
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) is a fluorescent analogue of phosphatidylcholine.
Anwendung
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) has been used in NBD-phospholipid translocation assay. It may be used as a molecular fluorescent marker to label lipids during the friction tests, as substrate for enzyme substrate specificity determination and in the preparation of small unilamellar vesicles.
Biochem./physiol. Wirkung
16:0-06:0 NBD PC (1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine) acts as a potential fluorescent probe. It is used for the quantification of the soluble and membrane-bound phospholipase A2 (PLA2) activity. 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) derivatives are widely used as fluorescent analogs of native lipids in biological and model membranes to study a variety of processes.
Verpackung
5 mL Amber Glass Screw Cap Vial (810130P-1mg)
5 mL Amber Glass Screw Cap Vial (810130P-5mg)
Rechtliche Hinweise
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Lagerklassenschlüssel
11 - Combustible Solids
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Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study
Biochimica et Biophysica Acta - Biomembranes, 1778(2), 491-501 (2008)
In vitro analysis of the Staphylococcus aureus lipoteichoic acid synthase enzyme using fluorescently labeled lipids
Journal of Bacteriology, 192(20), 5341-5349 (2010)
The use of C6-NBD-PC for assaying phospholipase A2-activity: scope and limitations
Biochimica et Biophysica Acta, Lipids and Lipid Metabolism, 1124(3), 223-232 (1992)
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PloS one, 7(10), e48437-e48437 (2012-11-03)
TRPV1 is a nonselective cation channel that integrates wide range of painful stimuli. It has been shown that its activity could be modulated by intracellular ligands PIP2 or calmodulin (CaM). The detailed localization and description of PIP2 interaction sites remain
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