699851P

3A-MPLA

Avanti Research^™ - A Croda Brand 699851P, powder

• Synonym(e): Monophosphoryl Tri-acyl Lipid A (Synthetic)
• Empirische Formel (Hill-System): C₅₄H₁₀₆N₃O₁₇P
• CAS-Nummer: 1699735-80-2
• Molekulargewicht: 1100.40
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (HPLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (699851P-1mg); pkg of 1 × 5 mg (699851P-5mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 699851P
• Anwendung(en): vaccine development
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2O.[NH4+]
• InChI: 1S/C54H103N2O17P.H3N/c1-4-7-10-13-16-19-20-23-26-29-32-35-46(61)70-41(34-31-28-25-22-18-15-12-9-6-3)37-45(60)56-48-51(64)52(73-74(66,67)68)42(38-57)72-54(48)69-39-43-49(62)50(63)47(53(65)71-43)55-44(59)36-40(58)33-30-27-24-21-17-14-11-8-5-2;/h40-43,47-54,

Beschreibung

Allgemeine Beschreibung

Monophosphoryl lipid A (MPLA) is an analog of the lipid A moiety. It is regarded as a detoxified derivative of the lipopolysaccharide (LPS).

Biochem./physiol. Wirkung

Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.

Verpackung

2 mL Amber Glass Crimp Cap Vial (699851P-1mg)

2 mL Amber Glass Crimp Cap Vial (699851P-5mg)

Sonstige Hinweise

For R&D use only. Not for drug, household, or other uses.

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available