QBD10850

Thiol-dPEG^®₁₂-acid

>95% (HPLC)

• Synonym(e): CT(PEG)₁₂, Carboxy-PEG-Thiol, Carboxy-PEG₁₂-Thiol, HS-PEG₁₂-COOH, Thiol-PEG₁₂-acid
• Empirische Formel (Hill-System): C₂₇H₅₄O₁₄S
• Molekulargewicht: 634.77
• MDL-Nummer: MFCD21363238
• UNSPSC-Code: 12162002
• NACRES: NA.22

Eigenschaften

• Assay: >95% (HPLC)
• Form: solid or viscous liquid
• Eignung der Reaktion: reaction type: Pegylations
• Polymerarchitektur: shape: linear; functionality: heterobifunctional
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Leistungsmerkmale und Vorteile

Thiol-dPEG₁₂-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long.

Rechtliche Hinweise

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable