QBD10008

Biotin-dPEG^®₁₂-TFP ester

• Synonym(e): Polyethylene glycol
• Empirische Formel (Hill-System): C₄₃H₆₉F₄N₃O₁₆S
• Molekulargewicht: 992.08
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 329823872
• NACRES: NA.22

Eigenschaften

• Assay: >90%
• Form: solid or viscous liquid
• Eignung der Reaktion: reaction type: Biotinylations; reaction type: Biotinylations; reactivity: amine reactive; reagent type: cross-linking reagent
• Polymerarchitektur: shape: linear; functionality: monofunctional
• Versandbedingung: ambient
• Lagertemp.: −20°C
• SMILES String: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)OC3=C(C(F)=CC(F)=C3F)F

Beschreibung

Leistungsmerkmale und Vorteile

Biotin-dPEG^®₁₂-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG^®₁₂-TFP ester has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Rechtliche Hinweise

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable